Dimethyl fumarate (DMFu) is a chemical used as an anti-mildew agent in some products, especially imported furniture and shoes. However, this substance can cause serious allergic reactions and therefore its use is limited or prohibited in many countries.

ISO/TS 16186 is a technical specification for the determination of dimethyl fumarate (DMFu). This technical specification describes methods and protocols used to detect and quantify dimethyl fumarate (DMFu).

We can summarize the general steps of this specification as follows:

1. **Sample Preparation:** Sampling and homogenizing the product to be tested.
2. **Extraction:** Extraction of dimethyl fumarate from the matrix of the sample with a suitable solvent.
3. **Analysis:** Analysis of the extract is usually done by gas chromatography (GC) or liquid chromatography (LC).
4. **Detection and Quantification:** The chromatograms obtained as a result of the analysis are examined, and the presence and amount of DMFu are determined.
5. **Evaluation of Results:** Obtained results are compared with reference standards and limit values.