Antiviral Activity Tests in Biocidal Products

Antiviral Activity Tests in Biocidal Products
What is a Biocidal Product?
Biocidal products are chemicals used to control or destroy harmful organisms (such as bacteria, viruses, fungi). These products have been developed to protect public health, ensure food safety and for use in various industrial applications.

Why Are Antiviral Activity Tests Important?
Antiviral effectiveness tests are performed to determine how effective biocidal products are against viruses. These tests are critical to ensuring the product's safety, effectiveness, and compliance with regulatory standards.

Types of Antiviral Activity Tests
General Test Methods
Antiviral activity tests can be performed by various methods. The most commonly used testing methods are:

 Cell Culture Tests
Monitoring Virus Proliferation in Cell Culture: This method measures the ability of viruses to multiply in cell cultures. Antiviral agents are determined by how effectively they prevent the virus from multiplying.
Plaque Assay: It is used to determine the number and size of plaques formed by viruses in cell cultures. Antiviral effectiveness is measured by the reduction in plaque number and size.
Enzymatic and Molecular Tests
Reverse Transcription Polymerase Chain Reaction (RT-PCR): It is used to detect and quantify the genetic materials of viruses. Antiviral activity is evaluated by the reduction in the amount of viral RNA/DNA.
Enzyme-Linked Immunosorbent Assay (ELISA): Used to detect and quantify virus proteins. Antiviral effectiveness is measured by the reduction of viral proteins.
Testing Procedures and Standards
EN 14476 Standard
EN 14476, European Standard, is a test method used to determine the effectiveness of biocidal products against viruses. This standard is especially valid for disinfectants used in the healthcare sector.

Test Conditions: Tests are carried out at a specified temperature and humidity conditions for a specified period of time.
Evaluation Criteria: A certain percentage reduction in the activity of the virus must be achieved.
ASTM E1053 Standard
ASTM E1053 is an American Standard used to measure the ability of biocidal products to inactivate viruses on surfaces.

Test Conditions: This test evaluates how effective the product is on inorganic surfaces.
Evaluation Criteria: The effectiveness of the product is determined by the reduction in the amount of virus.
Application Areas of Tests
Health sector
Hospitals and Clinics: Disinfectants and sterilization products are applied to equipment and surfaces used in hospital environments.
Medical Devices: Biocidal products are used for sterilization and disinfection of medical devices.
Food Industry
Food Processing Facilities: Biocidal products used to ensure food safety are used for surface disinfection and equipment sterilization.
Packaging: Disinfecting food packaging extends the shelf life of the product and prevents contamination.
Evaluation and Reporting of Test Results
Analysis of Data
Statistical Methods: Test results are evaluated with statistical analysis. These analyzes are used to determine the effectiveness of the product.
Control Groups: Control groups used in tests ensure the accuracy and reliability of the product's effect.
Reporting
Detailed Reports: Test results are presented in detailed reports. These reports provide information about the effectiveness and safety of the product.
Compliance with Regulations: Test results are evaluated for compliance with national and international regulations.
Conclusion
Antiviral efficacy tests are critical to determine the effectiveness of biocidal products against viruses. These tests are necessary to ensure the safety, effectiveness and compliance of products with regulatory standards. These tests are used to evaluate the effectiveness of biocidal products in the healthcare sector, food industry and many other fields.

As TTS LABORATORY SERVICES, we offer antiviral activity tests in accordance with national and international standards. You can contact us for detailed information and more information about our services.