Irritation Test in Biocidal Products ( OECD 439)

What is Skin Irritation?

Skin Irritation is defined as the production of reversible damage to the skin after exposure to chemicals contained in cosmetic or biocidal products.

Why Are Irritation Analyzes Performed?

The Skin Irritation Test is an in vitro non-animal test designed to distinguish between chemicals and mixtures that may cause moderate skin irritation.
Irritation caused by irritation in the skin and mucous membranes is a condition that should be examined especially in the use of biocidal and cosmetic products.

In Vitro OECD Test Guideline 439 Skin Irritation Test is performed in our laboratory using the in vitro Skin Irritation test method.

The epidermis is tested on 3D real human skins without using animals in vitro.

What are the Symptoms of Irritation on the Skin?

Skin reactions such as redness, swelling, inflammation or abrasion may occur.

Since biocidal products categorized as cosmetic products, disinfectants, preservatives and pest control are applied to human contact surfaces or directly to the skin, irritation tests must be performed.

Irritation testing procedures are generally based on exposing a reconstructed human epidermis (RhE) model to pure test chemical followed by determination of cell viability.

We are providing accredited service in our “Irritation Test” laboratory with the OECD Test Guideline 439 in vitro Skin Irritation test method.